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Synergistic antitumour activity of RAF265 and ZSTK474 on human TT medullary thyroid cancer cells

Medullary thyroid cancer (MTC) is an aggressive malignancy responsible for up to 14% of all thyroid cancer-related deaths. It is characterized by point mutations in the rearranged during transfection (RET) proto-oncogene. The activated RET kinase is known to signal via extracellular signal regulated...

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Detalles Bibliográficos
Autores principales: Bertazza, Loris, Barollo, Susi, Radu, Claudia Maria, Cavedon, Elisabetta, Simioni, Paolo, Faggian, Diego, Plebani, Mario, Pelizzo, Maria Rosa, Rubin, Beatrice, Boscaro, Marco, Pezzani, Raffaele, Mian, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568928/
https://www.ncbi.nlm.nih.gov/pubmed/26081844
http://dx.doi.org/10.1111/jcmm.12612