Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms

Genetic loss of collagen VII causes recessive dystrophic epidermolysis bullosa (RDEB)—a severe skin fragility disorder associated with lifelong blistering and disabling progressive soft tissue fibrosis. Causative therapies for this complex disorder face major hurdles, and clinical implementation rem...

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Detalles Bibliográficos
Autores principales: Nyström, Alexander, Thriene, Kerstin, Mittapalli, Venugopal, Kern, Johannes S, Kiritsi, Dimitra, Dengjel, Jörn, Bruckner-Tuderman, Leena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568953/
https://www.ncbi.nlm.nih.gov/pubmed/26194911
http://dx.doi.org/10.15252/emmm.201505061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568953/
https://www.ncbi.nlm.nih.gov/pubmed/26194911
http://dx.doi.org/10.15252/emmm.201505061

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