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The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration
Various neurodegenerative diseases are characterized by the accumulation of amyloidogenic proteins such as tau, α-synuclein, and amyloid-β. Prior to the formation of these stable aggregates, intermediate species of the respective proteins—oligomers—appear. Recently acquired data have shown that olig...
Autores principales: | Deger, Jennifer M, Gerson, Julia E, Kayed, Rakez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568959/ https://www.ncbi.nlm.nih.gov/pubmed/26053162 http://dx.doi.org/10.1111/acel.12359 |
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