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Ribosylation triggering Alzheimer’s disease-like Tau hyperphosphorylation via activation of CaMKII

Type 2 diabetes mellitus (T2DM) is regarded as one of the serious risk factors for age-related cognitive impairment; however, a causal link between these two diseases has so far not been established. It was recently discovered that, apart from high D-glucose levels, T2DM patients also display abnorm...

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Detalles Bibliográficos
Autores principales: Wei, Yan, Han, Chanshuai, Wang, Yujing, Wu, Beibei, Su, Tao, Liu, Ying, He, Rongqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568963/
https://www.ncbi.nlm.nih.gov/pubmed/26095350
http://dx.doi.org/10.1111/acel.12355