Massive Bioaccumulation and Self‐Assembly of Phenazine Compounds in Live Cells

Clofazimine is an orally administered drug that massively bioaccumulates in macrophages, forming membrane‐bound intracellular structures possessing nanoscale supramolecular features. Here, a library of phenazine compounds derived from clofazimine is synthesized and tested for ability to accumulate a...

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Detalles Bibliográficos
Autores principales: Min, Kyoung Ah, Rajeswaran, Walajapet G., Oldenbourg, Rudolf, Harris, Grant, Keswani, Rahul K., Chiang, Mason, Rzeczycki, Phillip, Talattof, Arjang, Hafeez, Mahwish, Horobin, Richard W., Larsen, Scott D., Stringer, Kathleen A., Rosania, Gus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569013/
https://www.ncbi.nlm.nih.gov/pubmed/26380168
http://dx.doi.org/10.1002/advs.201500025

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