Cargando…

Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers

OBJECTIVE: Recently, Next Generation Sequencing (NGS) has begun to supplant other technologies for gene mutation testing that is now required for targeted therapies. However, transfer of NGS technology to clinical daily practice requires validation. METHODS: We validated the Ion Torrent AmpliSeq Col...

Descripción completa

Detalles Bibliográficos
Autores principales:	D’Haene, Nicky, Le Mercier, Marie, De Nève, Nancy, Blanchard, Oriane, Delaunoy, Mélanie, El Housni, Hakim, Dessars, Barbara, Heimann, Pierre, Remmelink, Myriam, Demetter, Pieter, Tejpar, Sabine, Salmon, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569137/ https://www.ncbi.nlm.nih.gov/pubmed/26366557 http://dx.doi.org/10.1371/journal.pone.0138245

Ejemplares similares

Design and Validation of a Gene-Targeted, Next-Generation Sequencing Panel for Routine Diagnosis in Gliomas
por: D’Haene, Nicky, et al.
Publicado: (2019)

Clinical Application of Targeted Next Generation Sequencing for Colorectal Cancers
por: Fontanges, Quitterie, et al.
Publicado: (2016)

Clinical application of targeted next-generation sequencing for colorectal cancer patients: a multicentric Belgian experience
por: D’Haene, Nicky, et al.
Publicado: (2018)

Clinical, radiological and molecular characterization of intramedullary astrocytomas
por: Lebrun, Laetitia, et al.
Publicado: (2020)

Immunohistochemistry as an accurate tool for the assessment of BRAF V600E and TP53 mutations in primary and metastatic melanoma
por: Rusu, Stefan, et al.
Publicado: (2021)

The Prognostic Value of the Combination of Low VEGFR-1 and High VEGFR-2 Expression in Endothelial Cells of Colorectal Cancer
por: D’Haene, Nicky, et al.
Publicado: (2018)

Pancreatic Cancer Meets Human Microbiota: Close Encounters of the Third Kind
por: Arsenijevic, Tatjana, et al.
Publicado: (2021)

The daily practice reality of PD-L1 (CD274) evaluation in non-small cell lung cancer: A retrospective study
por: Verocq, Camille, et al.
Publicado: (2020)

A Novel Approach for Quantifying Cancer Cells Showing Hybrid Epithelial/Mesenchymal States in Large Series of Tissue Samples: Towards a New Prognostic Marker
por: Godin, Louis, et al.
Publicado: (2020)

Differentiated-Type Intraepithelial Neoplasia-Like Lesion Associated with Squamous Cell Carcinoma of the Anus: A Case Report with Molecular Profile
por: Koopmansch, Caroline, et al.
Publicado: (2019)

VEGFR1 and VEGFR2 Involvement in Extracellular Galectin-1- and Galectin-3-Induced Angiogenesis
por: D'Haene, Nicky, et al.
Publicado: (2013)

PIK3CA and p53 Mutations by Next Generation Sequencing in Lymphoepithelioma-Like Carcinoma of the Endometrium
por: Bienfait, Lucie, et al.
Publicado: (2018)

IGF-IR: a new prognostic biomarker for human glioblastoma
por: Maris, C, et al.
Publicado: (2015)

Borderline phyllodes tumour of the breast with eosinophilic inclusion bodies: Case report and molecular sequencing
por: Lam, Ngoc My, et al.
Publicado: (2023)

A Two-Step Diagnostic Approach for NTRK Gene Fusion Detection in Biliary Tract and Pancreatic Adenocarcinomas
por: Demols, Anne, et al.
Publicado: (2023)

Low grade malignant eccrine spiradenoma of the vulva: case report, review of the literature and discussion about the role of p53 and HPV
por: Catteau, Xavier, et al.
Publicado: (2020)

Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients
por: Maréchal, Raphaël, et al.
Publicado: (2010)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Genome Sequencing from Post-Mortem Formalin-Fixed, Paraffin-Embedded Lung Tissues
por: Van Campenhout, Claude, et al.
Publicado: (2021)

SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature
por: Lebrun, Laetitia, et al.
Publicado: (2023)

Osseous Metaplasia in Low-grade Ovarian Serous Carcinoma With a BRAF Mutation: A Case Report
por: Catteau, Xavier, et al.
Publicado: (2021)

First Report on Fetal Cerebral Polyglucosan Bodies in Mucopolysaccharidosis Type VII
por: Kadhim, Hazim, et al.
Publicado: (2017)

Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients
por: Remmelink, Myriam, et al.
Publicado: (2020)

Analyses of DNA Methylation Profiling in the Diagnosis of Intramedullary Astrocytomas
por: Lebrun, Laetitia, et al.
Publicado: (2021)

P53 and PIK3CA Mutations in KRAS/HER2 Negative Ovarian Intestinal-Type Mucinous Carcinoma Associated with Mature Teratoma
por: Bouri, Sarah, et al.
Publicado: (2020)

Invasive ductal carcinoma arising in borderline phyllode tumor: A potential role of PIK3CA mutation
por: Bouri, Sarah, et al.
Publicado: (2020)

First Case Report of a Uterine Angiolipoleiomyoma With KRAS and KIT Mutations
por: Verocq, Camille, et al.
Publicado: (2022)

Undetectable circulating tumor DNA (ctDNA) levels correlate with favorable outcome in metastatic melanoma patients treated with anti-PD1 therapy
por: Seremet, Teofila, et al.
Publicado: (2019)

Infections gastro-intestinales chez le patient immunocompromis
por: Nagy, Nathalie, et al.
Publicado: (2002)

Interpreting the impact of noncoding structural variation in neurodevelopmental disorders
por: D’haene, Eva, et al.
Publicado: (2020)

TP53, ATRX alterations, and low tumor mutation load feature IDH-wildtype giant cell glioblastoma despite exceptional ultra-mutated tumors
por: Cantero, Diana, et al.
Publicado: (2020)

The Role of SMAD4 Inactivation in Epithelial–Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link?
por: Racu, Marie-Lucie, et al.
Publicado: (2022)

SMAD4 Positive Pancreatic Ductal Adenocarcinomas Are Associated with Better Outcomes in Patients Receiving FOLFIRINOX-Based Neoadjuvant Therapy
por: Racu, Marie-Lucie, et al.
Publicado: (2023)

Fasting, food and farming: Value chains and food taboos in Ethiopia
por: D’Haene, Eline, et al.
Publicado: (2021)

Mimicking and anticipating others’ actions is linked to Social Information Processing
por: Genschow, Oliver, et al.
Publicado: (2018)

Case report: BRAF A598-T599insV mutation as a potential resistance mechanism to alectinib in ALK-rearranged lung adenocarcinoma
por: Pasau, Thomas, et al.
Publicado: (2022)

KRAS Mutation in Serous Borderline Tumor of the Testis: Report of a Case and Review of the Literature
por: Bouri, Sarah, et al.
Publicado: (2020)

Identification of long non-coding RNAs involved in neuronal development and intellectual disability
por: D’haene, Eva, et al.
Publicado: (2016)

Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
por: De Smedt, L, et al.
Publicado: (2015)

Beneficial Effects of Tacrolimus on Brain-Death-Associated Right Ventricular Dysfunction in Pigs
por: Belhaj, Asmae, et al.
Publicado: (2023)

Diagnostic value of the UCA1 test for bladder cancer detection: a clinical study
por: Milowich, Dina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_dn3qn06ivqhd4tmr9jovinec8u