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Continued Follow-Up of Phambili Phase 2b Randomized HIV-1 Vaccine Trial Participants Supports Increased HIV-1 Acquisition among Vaccinated Men

BACKGROUND: The Phase 2b double-blinded, randomized Phambili/HVTN 503 trial evaluated safety and efficacy of the MRK Ad5 gag/pol/nef subtype B HIV-1 preventive vaccine vs placebo in sexually active HIV-1 seronegative participants in South Africa. Enrollment and vaccinations stopped and participants...

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Detalles Bibliográficos
Autores principales: Moodie, Zoe, Metch, Barbara, Bekker, Linda-Gail, Churchyard, Gavin, Nchabeleng, Maphoshane, Mlisana, Koleka, Laher, Fatima, Roux, Surita, Mngadi, Kathryn, Innes, Craig, Mathebula, Matsontso, Allen, Mary, Bentley, Carter, Gilbert, Peter B., Robertson, Michael, Kublin, James, Corey, Lawrence, Gray, Glenda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569275/
https://www.ncbi.nlm.nih.gov/pubmed/26368824
http://dx.doi.org/10.1371/journal.pone.0137666