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TIMP-1 Inhibits Apoptosis in Lung Adenocarcinoma Cells via Interaction with Bcl-2

Tissue inhibitors of metalloproteinases (TIMPs) are multifaceted molecules that exhibit properties beyond their classical proteinase inhibitory function. Although TIMP-1 is a known inhibitor of apoptosis in mammalian cells, the mechanisms by which it exerts its effects are not well-established. Our...

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Detalles Bibliográficos
Autores principales: Nalluri, Srilatha, Ghoshal-Gupta, Sampa, Kutiyanawalla, Ammar, Gayatri, Sitaram, Lee, Byung Rho, Jiwani, Shahanawaz, Rojiani, Amyn M., Rojiani, Mumtaz V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569297/
https://www.ncbi.nlm.nih.gov/pubmed/26366732
http://dx.doi.org/10.1371/journal.pone.0137673