The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis

Viral fulminant hepatitis (FH) is a severe disease with high mortality resulting from excessive inflammation in the infected liver. Clinical interventions have been inefficient due to the lack of knowledge for inflammatory pathogenesis in the virus-infected liver. We show that wild-type mice infecte...

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Detalles Bibliográficos
Autores principales: Guo, Sheng, Yang, Chengying, Diao, Bo, Huang, Xiaoyong, Jin, Meihua, Chen, Lili, Yan, Weiming, Ning, Qin, Zheng, Lixin, Wu, Yuzhang, Chen, Yongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569300/
https://www.ncbi.nlm.nih.gov/pubmed/26367131
http://dx.doi.org/10.1371/journal.ppat.1005155

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