Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs

S. aureus vaccine development has proven particularly difficult. The conventional approach to achieve sterile immunity through opsonophagocytic killing has been largely unsuccessful. S. aureus is highly toxigenic and a great body of evidence suggests that a successful future vaccine for this organis...

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Detalles Bibliográficos
Autores principales: Adhikari, Rajan P., Kort, Thomas, Shulenin, Sergey, Kanipakala, Tulasikumari, Ganjbaksh, Nader, Roghmann, Mary-Claire, Holtsberg, Frederick W., Aman, M. Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569305/
https://www.ncbi.nlm.nih.gov/pubmed/26367030
http://dx.doi.org/10.1371/journal.pone.0137874

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