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Tumor necrosis factor–related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotype

Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is a promising candidate for cancer therapy, because it can induce apoptosis in various tumor cells but not in most normal cells. Although it is well known that TRAIL and its receptors are expressed in many types of normal cells, includ...

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Detalles Bibliográficos
Autores principales: Gao, Jing, Wang, Dongsheng, Liu, Dan, Liu, Min, Ge, Yehua, Jiang, Minghong, Liu, Yanxin, Zheng, Dexian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569310/
https://www.ncbi.nlm.nih.gov/pubmed/26224317
http://dx.doi.org/10.1091/mbc.E15-04-0209