TPC2 mediates new mechanisms of platelet dense granule membrane dynamics through regulation of Ca(2+) release

Platelet dense granules (PDGs) are acidic calcium stores essential for normal hemostasis. They develop from late endosomal compartments upon receiving PDG-specific proteins through vesicular trafficking, but their maturation process is not well understood. Here we show that two-pore channel 2 (TPC2)...

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Detalles Bibliográficos
Autores principales: Ambrosio, Andrea L., Boyle, Judith A., Di Pietro, Santiago M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569316/
https://www.ncbi.nlm.nih.gov/pubmed/26202466
http://dx.doi.org/10.1091/mbc.E15-01-0058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569316/
https://www.ncbi.nlm.nih.gov/pubmed/26202466
http://dx.doi.org/10.1091/mbc.E15-01-0058

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