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ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer

Several studies have suggested ERBB3/HER3 may be a useful prognostic marker for colorectal cancer. Tumours with an intestinal stem cell signature have also been shown to be more aggressive. Here, we investigate whether ERBB3 is associated with intestinal stem cell markers in colorectal cancer and if...

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Detalles Bibliográficos
Autores principales: Jardé, Thierry, Kass, Lisa, Staples, Margaret, Lescesen, Helen, Carne, Peter, Oliva, Karen, McMurrick, Paul J., Abud, Helen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569358/
https://www.ncbi.nlm.nih.gov/pubmed/26367378
http://dx.doi.org/10.1371/journal.pone.0138336