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Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis
Bipotent axial stem cells residing in the caudal epiblast during late gastrulation generate neuroectodermal and presomitic mesodermal progeny that coordinate somitogenesis with neural tube formation, but the mechanism that controls these two fates is not fully understood. Retinoic acid (RA) restrict...
Autores principales: | Cunningham, Thomas J., Brade, Thomas, Sandell, Lisa L., Lewandoski, Mark, Trainor, Paul A., Colas, Alexandre, Mercola, Mark, Duester, Gregg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569375/ https://www.ncbi.nlm.nih.gov/pubmed/26368825 http://dx.doi.org/10.1371/journal.pone.0137894 |
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