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Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells
Differential redox homeostasis in normal and malignant cells suggests that pro-oxidant-induced upregulation of cellular reactive oxygen species (ROS) should selectively target cancer cells without compromising the viability of untransformed cells. Consequently, a pro-oxidant deviation well-tolerated...
Autores principales: | González-Bártulos, Marta, Aceves-Luquero, Clara, Qualai, Jamal, Cussó, Olaf, Martínez, Mª Angeles, Fernández de Mattos, Silvia, Menéndez, Javier A., Villalonga, Priam, Costas, Miquel, Ribas, Xavi, Massaguer, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569415/ https://www.ncbi.nlm.nih.gov/pubmed/26368127 http://dx.doi.org/10.1371/journal.pone.0137800 |
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