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A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Metformin Therapy in Overweight/Obese Youth with Type 1 Diabetes

CONTEXT: Insulin resistance has been proposed as one of the causes of poor glycemic control in overweight/obese youth with type 1 diabetes (T1D). However, the role of adjunctive metformin, an insulin sensitizer, on glycemic control in these patients is unclear. OBJECTIVE: To compare the effect of me...

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Detalles Bibliográficos
Autores principales: Nwosu, Benjamin Udoka, Maranda, Louise, Cullen, Karen, Greenman, Lisa, Fleshman, Jody, McShea, Nancy, Barton, Bruce A., Lee, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569440/
https://www.ncbi.nlm.nih.gov/pubmed/26367281
http://dx.doi.org/10.1371/journal.pone.0137525