Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls

Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three...

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Detalles Bibliográficos
Autores principales: Niu, Zhenmin, Wang, Jiucun, Zou, Hejian, Yang, Chengde, Huang, Wei, Jin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569555/
https://www.ncbi.nlm.nih.gov/pubmed/26366721
http://dx.doi.org/10.1371/journal.pone.0137770
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author Niu, Zhenmin
Wang, Jiucun
Zou, Hejian
Yang, Chengde
Huang, Wei
Jin, Li
author_facet Niu, Zhenmin
Wang, Jiucun
Zou, Hejian
Yang, Chengde
Huang, Wei
Jin, Li
author_sort Niu, Zhenmin
collection PubMed
description Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three common SNPs: rs2910164, rs2431697 and rs57095329 were selected and genotyped in 611 patients and 617 controls. We found no association between these SNPs and ankylosing spondylitis in our samples.
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spelling pubmed-45695552015-09-18 Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls Niu, Zhenmin Wang, Jiucun Zou, Hejian Yang, Chengde Huang, Wei Jin, Li PLoS One Research Article Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three common SNPs: rs2910164, rs2431697 and rs57095329 were selected and genotyped in 611 patients and 617 controls. We found no association between these SNPs and ankylosing spondylitis in our samples. Public Library of Science 2015-09-14 /pmc/articles/PMC4569555/ /pubmed/26366721 http://dx.doi.org/10.1371/journal.pone.0137770 Text en © 2015 Niu et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Niu, Zhenmin
Wang, Jiucun
Zou, Hejian
Yang, Chengde
Huang, Wei
Jin, Li
Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls
title Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls
title_full Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls
title_fullStr Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls
title_full_unstemmed Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls
title_short Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls
title_sort common mir146a polymorphisms in chinese ankylosing spondylitis subjects and controls
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569555/
https://www.ncbi.nlm.nih.gov/pubmed/26366721
http://dx.doi.org/10.1371/journal.pone.0137770
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