Sphingosine-1-Phosphate Receptor-1 Selective Agonist Enhances Collateral Growth and Protects against Subsequent Stroke

BACKGROUND AND PURPOSE: Collateral growth after acute occlusion of an intracranial artery is triggered by increasing shear stress in preexisting collateral pathways. Recently, sphingosine-1-phosphate receptor-1 (S1PR1) on endothelial cells was reported to be essential in sensing fluid shear stress....

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Detalles Bibliográficos
Autores principales: Ichijo, Masahiko, Ishibashi, Satoru, Li, Fuying, Yui, Daishi, Miki, Kazunori, Mizusawa, Hidehiro, Yokota, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569572/
https://www.ncbi.nlm.nih.gov/pubmed/26367258
http://dx.doi.org/10.1371/journal.pone.0138029

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