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ProNGF derived from rat sciatic nerves downregulates neurite elongation and axon specification in PC12 cells

Several reports have shown that a sciatic nerve conditioned media (CM) causes neuronal-like differentiation in PC12 cells. This differentiation is featured by neurite outgrowth, which are exclusively dendrites, without axon or sodium current induction. In previous studies, our group reported that th...

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Detalles Bibliográficos
Autores principales: Trigos, Anna Sofía, Longart, Marines, García, Lisbeth, Castillo, Cecilia, Forsyth, Patricia, Medina, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569732/
https://www.ncbi.nlm.nih.gov/pubmed/26441535
http://dx.doi.org/10.3389/fncel.2015.00364