Cargando…

A quantitative description of Ndc80 complex linkage to human kinetochores

The Ndc80 complex, which mediates end-on attachment of spindle microtubules, is linked to centromeric chromatin in human cells by two inner kinetochore proteins, CENP-T and CENP-C. Here to quantify their relative contributions to Ndc80 recruitment, we combine measurements of kinetochore protein copy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suzuki, Aussie, Badger, Benjamin L., Salmon, Edward D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569735/ https://www.ncbi.nlm.nih.gov/pubmed/26345214 http://dx.doi.org/10.1038/ncomms9161

Ejemplares similares

The Ndc80 complex targets Bod1 to human mitotic kinetochores
por: Schleicher, Katharina, et al.
Publicado: (2017)

Multi-modal microtubule binding by the Ndc80 kinetochore complex
por: Alushin, Gregory M., et al.
Publicado: (2012)

Stable kinetochore‐microtubule attachment requires loop‐dependent Ndc80‐Ndc80 binding
por: Polley, Soumitra, et al.
Publicado: (2023)

The Ndc80 kinetochore complex forms oligomeric arrays along microtubules
por: Alushin, Gregory M., et al.
Publicado: (2010)

Structure of the Ndc80 complex and its interactions at the yeast kinetochore–microtubule interface
por: Zahm, Jacob A., et al.
Publicado: (2023)

Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation
por: Sarangapani, Krishna K., et al.
Publicado: (2021)

Recruitment of two Ndc80 complexes via the CENP-T pathway is sufficient for kinetochore functions
por: Takenoshita, Yusuke, et al.
Publicado: (2022)

Molecular requirements for the formation of a kinetochore–microtubule interface by Dam1 and Ndc80 complexes
por: Lampert, Fabienne, et al.
Publicado: (2013)

Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80
por: Kern, David M, et al.
Publicado: (2017)

The Dam1 complex confers microtubule plus end–tracking activity to the Ndc80 kinetochore complex
por: Lampert, Fabienne, et al.
Publicado: (2010)

Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B
por: Tien, Jerry F., et al.
Publicado: (2010)

Aurora B-dependent Ndc80 degradation regulates kinetochore composition in meiosis
por: Chen, Jingxun, et al.
Publicado: (2020)

Hec1/Ndc80 Tail Domain Function at the Kinetochore-Microtubule Interface
por: Wimbish, Robert T., et al.
Publicado: (2020)

How the kinetochore couples microtubule force and centromere stretch to move chromosomes
por: Suzuki, Aussie, et al.
Publicado: (2016)

Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore–microtubule attachments
por: Helgeson, Luke A., et al.
Publicado: (2018)

Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces
por: Volkov, Vladimir A, et al.
Publicado: (2018)

Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly
por: Dong, Qianhua, et al.
Publicado: (2021)

The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit
por: Rahi, Amit, et al.
Publicado: (2023)

The Hec1/Ndc80 tail domain is required for force generation at kinetochores, but is dispensable for kinetochore–microtubule attachment formation and Ska complex recruitment
por: Wimbish, Robert T., et al.
Publicado: (2020)

An optimized method for 3D fluorescence co-localization applied to human kinetochore protein architecture
por: Suzuki, Aussie, et al.
Publicado: (2018)

The Ndc80 Loop Region Facilitates Formation of Kinetochore Attachment to the Dynamic Microtubule Plus End
por: Maure, Jean-François, et al.
Publicado: (2011)

Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments
por: Yoo, Tae Yeon, et al.
Publicado: (2018)

Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80
por: Pesenti, Marion E., et al.
Publicado: (2018)

The NDC80 complex proteins Nuf2 and Hec1 make distinct contributions to kinetochore–microtubule attachment in mitosis
por: Sundin, Lynsie J.R., et al.
Publicado: (2011)

Coordination between the Ndc80 complex and dynein is essential for microtubule plus-end capture by kinetochores during early mitosis
por: Amin, Mohammed Abdullahel, et al.
Publicado: (2023)

The hairpin region of Ndc80 is important for the kinetochore recruitment of Mph1/MPS1 in fission yeast
por: Chmielewska, Aldona Ewa, et al.
Publicado: (2016)

Orientation and structure of the Ndc80 complex on the microtubule lattice
por: Wilson-Kubalek, Elizabeth M., et al.
Publicado: (2008)

Purification and characterisation of the fission yeast Ndc80 complex
por: Matsuo, Yuzy, et al.
Publicado: (2017)

Meiotic regulation of the Ndc80 complex composition and function
por: Chen, Jingxun, et al.
Publicado: (2021)

Effect of NDC80 in human hepatocellular carcinoma
por: Ju, Lin-Ling, et al.
Publicado: (2017)

The Ndc80 complex bridges two Dam1 complex rings
por: Kim, Jae ook, et al.
Publicado: (2017)

Ndc80 Internal Loop Interacts with Dis1/TOG to Ensure Proper Kinetochore-Spindle Attachment in Fission Yeast
por: Hsu, Kuo-Shun, et al.
Publicado: (2011)

Strain stiffening of Ndc80 complexes attached to microtubule plus ends
por: Schwietert, Felix, et al.
Publicado: (2022)

Vertebrate kinetochore protein architecture: protein copy number
por: Johnston, Katherine, et al.
Publicado: (2010)

MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation
por: Tang, Ngang Heok, et al.
Publicado: (2015)

Ndc10 is a platform for inner kinetochore assembly in budding yeast
por: Cho, Uhn-Soo, et al.
Publicado: (2011)

Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation
por: Montpetit, Ben, et al.
Publicado: (2006)

Alp7/TACC recruits kinesin-8–PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement
por: Tang, Ngang Heok, et al.
Publicado: (2015)

Potential therapeutic targets of the nuclear division cycle 80 (NDC80) complexes genes in lung adenocarcinoma
por: Sun, Zhong-Yi, et al.
Publicado: (2020)

Tight bending of the Ndc80 complex provides intrinsic regulation of its binding to microtubules
por: Scarborough, Emily Anne, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t0afhqm1862nqa9hecbks92198