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Activation and cytokine profile of monocyte derived dendritic cells in leprosy: in vitro stimulation by sonicated Mycobacterium leprae induces decreased level of IL-12p70 in lepromatous leprosy
Dendritic cells (DCs) play a pivotal role in the connection of innate and adaptive immunity of hosts to mycobacterial infection. Studies on the interaction of monocyte-derived DCs (MO-DCs) using Mycobacterium leprae in leprosy patients are rare. The present study demonstrated that the differentiatio...
Autores principales: | Braga, André Flores, Moretto, Daniela Ferraz, Gigliotti, Patrícia, Peruchi, Mariela, Vilani-Moreno, Fátima Regina, Campanelli, Ana Paula, Latini, Ana Carla Pereira, Iyer, Anand, Das, Pranab Kumar, de Souza, Vânia Nieto Brito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569830/ https://www.ncbi.nlm.nih.gov/pubmed/26222022 http://dx.doi.org/10.1590/0074-02760140230 |
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