Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis

An unexpectedly extensive recruitment of B cells and plasma blasts to the cerebrospinal fluid (CSF) in a patient with Toscana virus (TOSV) encephalitis is described. Acute infection by TOSV was demonstrated by serological methods and by detection of TOSV-specific nucleic acid in the CSF by real-time...

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Autores principales: Schirmer, Lucas, Wölfel, Silke, Georgi, Enrico, Ploner, Markus, Bauer, Barbara, Hemmer, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569839/
https://www.ncbi.nlm.nih.gov/pubmed/26393235
http://dx.doi.org/10.1093/ofid/ofv124
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author Schirmer, Lucas
Wölfel, Silke
Georgi, Enrico
Ploner, Markus
Bauer, Barbara
Hemmer, Bernhard
author_facet Schirmer, Lucas
Wölfel, Silke
Georgi, Enrico
Ploner, Markus
Bauer, Barbara
Hemmer, Bernhard
author_sort Schirmer, Lucas
collection PubMed
description An unexpectedly extensive recruitment of B cells and plasma blasts to the cerebrospinal fluid (CSF) in a patient with Toscana virus (TOSV) encephalitis is described. Acute infection by TOSV was demonstrated by serological methods and by detection of TOSV-specific nucleic acid in the CSF by real-time polymerase chain reaction and sequencing.
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spelling pubmed-45698392015-09-21 Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis Schirmer, Lucas Wölfel, Silke Georgi, Enrico Ploner, Markus Bauer, Barbara Hemmer, Bernhard Open Forum Infect Dis Brief Reports An unexpectedly extensive recruitment of B cells and plasma blasts to the cerebrospinal fluid (CSF) in a patient with Toscana virus (TOSV) encephalitis is described. Acute infection by TOSV was demonstrated by serological methods and by detection of TOSV-specific nucleic acid in the CSF by real-time polymerase chain reaction and sequencing. Oxford University Press 2015-09-01 /pmc/articles/PMC4569839/ /pubmed/26393235 http://dx.doi.org/10.1093/ofid/ofv124 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Schirmer, Lucas
Wölfel, Silke
Georgi, Enrico
Ploner, Markus
Bauer, Barbara
Hemmer, Bernhard
Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis
title Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis
title_full Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis
title_fullStr Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis
title_full_unstemmed Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis
title_short Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis
title_sort extensive recruitment of plasma blasts to the cerebrospinal fluid in toscana virus encephalitis
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569839/
https://www.ncbi.nlm.nih.gov/pubmed/26393235
http://dx.doi.org/10.1093/ofid/ofv124
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