Cargando…

Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR

Specific arrestin conformations are coupled to distinct downstream effectors, which underlie the functions of many G-protein-coupled receptors (GPCRs). Here, using unnatural amino acid incorporation and fluorine-19 nuclear magnetic resonance ((19)F-NMR) spectroscopy, we demonstrate that distinct rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Fan, Yu, Xiao, Liu, Chuan, Qu, Chang-Xiu, Gong, Zheng, Liu, Hong-Da, Li, Fa-Hui, Wang, Hong-Mei, He, Dong-Fang, Yi, Fan, Song, Chen, Tian, Chang-Lin, Xiao, Kun-Hong, Wang, Jiang-Yun, Sun, Jin-Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569848/ https://www.ncbi.nlm.nih.gov/pubmed/26347956 http://dx.doi.org/10.1038/ncomms9202

Ejemplares similares

DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl (1)H-NMR probe
por: Liu, Qi, et al.
Publicado: (2020)

Genetic Incorporation of Unnatural Amino Acids into Proteins in Mycobacterium tuberculosis
por: Wang, Feng, et al.
Publicado: (2010)

Advances and Challenges in Cell-Free Incorporation of Unnatural Amino Acids Into Proteins
por: Gao, Wei, et al.
Publicado: (2019)

Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids
por: Drienovská, Ivana, et al.
Publicado: (2015)

RF1 Knockout Allows Ribosomal Incorporation of Unnatural Amino Acids at Multiple Sites
por: Johnson, David B.F., et al.
Publicado: (2011)

A linear DNA template-based framework for site-specific unnatural amino acid incorporation
por: Chen, Xinjie, et al.
Publicado: (2021)

Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid
por: Yu, Yang, et al.
Publicado: (2015)

Using genetically incorporated unnatural amino acids to control protein functions in mammalian cells
por: Nödling, Alexander R., et al.
Publicado: (2019)

Efficient Incorporation of Unnatural Amino Acids into Proteins with a Robust Cell-Free System
por: Gao, Wei, et al.
Publicado: (2019)

The Benefits of Unnatural Amino Acid Incorporation as Protein Labels for Single Molecule Localization Microscopy
por: Laxman, Pooja, et al.
Publicado: (2021)

Phosphorylation-induced conformation of β(2)-adrenoceptor related to arrestin recruitment revealed by NMR
por: Shiraishi, Yutaro, et al.
Publicado: (2018)

Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction
por: Zhao, Hongxia, et al.
Publicado: (2021)

Toward efficient multiple-site incorporation of unnatural amino acids using cell-free translation system
por: Hou, Jiaqi, et al.
Publicado: (2021)

Unnatural amino acid incorporation in E. coli: current and future applications in the design of therapeutic proteins
por: Wals, Kim, et al.
Publicado: (2014)

Tunable translational control using site-specific unnatural amino acid incorporation in Escherichia coli
por: Kato, Yusuke
Publicado: (2015)

Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification
por: Rowan, Fiona C., et al.
Publicado: (2013)

Rational incorporation of any unnatural amino acid into proteins by machine learning on existing experimental proofs
por: Zhang, Haoran, et al.
Publicado: (2022)

Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling
por: Liu, Chun-Hua, et al.
Publicado: (2017)

P19-09. Site-specific incorporation of an unnatural amino acid into the HIV-1 Env spike
por: Arnett, SO, et al.
Publicado: (2009)

Crucial Optimization of Translational Components towards Efficient Incorporation of Unnatural Amino Acids into Proteins in Mammalian Cells
por: Xiang, Liang, et al.
Publicado: (2013)

Reinitiation at non-canonical start codons leads to leak expression when incorporating unnatural amino acids
por: Kalstrup, Tanja, et al.
Publicado: (2015)

Controlling the interaction between CaMKII and Calmodulin with a photocrosslinking unnatural amino acid
por: Lučić, Iva, et al.
Publicado: (2023)

A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids
por: Ieong, Ka-Weng, et al.
Publicado: (2014)

Development of a Novel Q-body Using an In Vivo Site-Specific Unnatural Amino Acid Incorporation System
por: Kurumida, Yoichi, et al.
Publicado: (2018)

Modified Peptide Inhibitors of the Keap1–Nrf2 Protein–Protein Interaction Incorporating Unnatural Amino Acids
por: Georgakopoulos, Nikolaos D., et al.
Publicado: (2018)

Site-Specific Incorporation of Unnatural Amino Acids into Escherichia coli Recombinant Protein: Methodology Development and Recent Achievement
por: Smolskaya, Sviatlana, et al.
Publicado: (2019)

FRI162 Ligand-dependent Photocrosslinking of Mineralocorticoid Receptors Using Site-directed Incorporation of Unnatural Amino Acids
por: Almeida-Prieto, Brian, et al.
Publicado: (2023)

Studies on the Incorporation of an Unnatural Amino Acid, p-DI-(2-Hydroxy[(14)C(2)]Ethyl) Amino-L-Phenylalanine, into Proteins
por: Brookes, P.
Publicado: (1959)

Fluorescence Modulation of Green Fluorescent Protein Using Fluorinated Unnatural Amino Acids
por: Villa, Jordan K., et al.
Publicado: (2017)

Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs
por: Yu, Yang, et al.
Publicado: (2015)

Unnatural amino acids: better than the real things?
por: Minnihan, Ellen C, et al.
Publicado: (2009)

Exploring the role of unnatural amino acids in antimicrobial peptides
por: Oliva, Rosario, et al.
Publicado: (2018)

Synthesis of complex unnatural fluorine-containing amino acids
por: Brittain, William D.G., et al.
Publicado: (2020)

Reprogramming natural proteins using unnatural amino acids
por: Adhikari, Anup, et al.
Publicado: (2021)

Cell-Free Expression of Unnatural Amino Acid Incorporated Aquaporin SS9 with Improved Separation Performance in Biomimetic Membranes
por: Wei, Peilian, et al.
Publicado: (2018)

Study and design of amino acid-based radical enzymes using unnatural amino acids
por: Yuan, Feiyan, et al.
Publicado: (2023)

Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET
por: Perdios, Louis, et al.
Publicado: (2017)

Conditional knockout tools: Application of site-specific incorporation of unnatural amino acid via genetic code expansion in viral and parasite vaccine development
por: Liu, Pinghua, et al.
Publicado: (2017)

A genetically encoded multifunctional unnatural amino acid for versatile protein manipulations in living cells
por: Ge, Yun, et al.
Publicado: (2016)

Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide
por: Singh, Isha, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_01dq5iokp53dl1kebq1aei21v0