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Mechanisms of Kidney Injury in Lupus Nephritis – the Role of Anti-dsDNA Antibodies
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a breakdown of self-tolerance, production of auto-antibodies and immune-mediated injury, resulting in damage accrual in multiple organs. Kidney involvement, termed lupus nephritis, is a major cause of morbidity and mortalit...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569852/ https://www.ncbi.nlm.nih.gov/pubmed/26441980 http://dx.doi.org/10.3389/fimmu.2015.00475 |