Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity

Both caloric restriction (CR) and resveratrol (RSV) have beneficial effects on obesity. However, the biochemical pathways that mediate these beneficial effects might be complex and interconnected and have not been fully elucidated. To reveal the common therapeutic mechanism of CR and RSV, we perform...

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Detalles Bibliográficos
Autores principales: Nishimura, Yuhei, Sasagawa, Shota, Ariyoshi, Michiko, Ichikawa, Sayuri, Shimada, Yasuhito, Kawaguchi, Koki, Kawase, Reiko, Yamamoto, Reiko, Uehara, Takuma, Yanai, Takaaki, Takata, Ryoji, Tanaka, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569862/
https://www.ncbi.nlm.nih.gov/pubmed/26441656
http://dx.doi.org/10.3389/fphar.2015.00199

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