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Liver abscess as a first manifestation of colonic tumor

INTRODUCTION: Male, 72-year-old, morbidly obese, diabetic, admitted for abdominal pain, prostration and fever that started last 3 days. Abdominal ultrasound and abdominal computed tomography scan showed liver injury in the transition of V and VI segments measuring 8.4 cm. Due to the possibility of l...

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Autores principales: Schneider, N. Camargo, Coelho, N., Dutra, P., Dalmolin, R., Dincao, R., Appel, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569906/
https://www.ncbi.nlm.nih.gov/pubmed/26425508
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author Schneider, N. Camargo
Coelho, N.
Dutra, P.
Dalmolin, R.
Dincao, R.
Appel, M.
author_facet Schneider, N. Camargo
Coelho, N.
Dutra, P.
Dalmolin, R.
Dincao, R.
Appel, M.
author_sort Schneider, N. Camargo
collection PubMed
description INTRODUCTION: Male, 72-year-old, morbidly obese, diabetic, admitted for abdominal pain, prostration and fever that started last 3 days. Abdominal ultrasound and abdominal computed tomography scan showed liver injury in the transition of V and VI segments measuring 8.4 cm. Due to the possibility of liver abscess, initiate empirical antibiotic therapy with ampicillin and sulbactam and metronidazole and performed ultrasound-guided percutaneous drainage of liver injury. Negative for malignant cells, with the presence of leukocytes and negative culture. After 2 weeks of treatment, take control image without changing the lesion dimension. New percutaneous drainage with the same results. We opted for performing endoscopic ultrasound (EUS) with fine-needle aspiration (FNA). FNA pathology: Moderately differentiated adenocarcinoma. Immunohistochemistry suggestive of metastasis of the lower gastrointestinal tract. Due this finding, realized colonoscopy, which revealed a vegetating lesion with central ulceration, bleeding, filling almost the entire cecum. Patient was referred for surgical resection of the bowel tumor, which showed moderately differentiated adenocarcinoma infiltrating vegetative and possibly originated from villous adenoma with high-grade dysplasia. DISCUSSION: The finding of metastatic liver abscess of colonic neoplasia is not common. In most cases, the material from the abscess drainage allows the diagnosis, but in this case, even after two ultrasound-guided percutaneous drainage was not obtained conclusive bacteriological or histopathological. Opted for new puncture through EUS, which allowed definitive diagnosis of the condition. CONCLUSION: Metastatic colon neoplasm should be considered in cases of differential diagnosis of liver abscess.
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spelling pubmed-45699062015-09-30 Liver abscess as a first manifestation of colonic tumor Schneider, N. Camargo Coelho, N. Dutra, P. Dalmolin, R. Dincao, R. Appel, M. Endosc Ultrasound EURO EUS Meeting INTRODUCTION: Male, 72-year-old, morbidly obese, diabetic, admitted for abdominal pain, prostration and fever that started last 3 days. Abdominal ultrasound and abdominal computed tomography scan showed liver injury in the transition of V and VI segments measuring 8.4 cm. Due to the possibility of liver abscess, initiate empirical antibiotic therapy with ampicillin and sulbactam and metronidazole and performed ultrasound-guided percutaneous drainage of liver injury. Negative for malignant cells, with the presence of leukocytes and negative culture. After 2 weeks of treatment, take control image without changing the lesion dimension. New percutaneous drainage with the same results. We opted for performing endoscopic ultrasound (EUS) with fine-needle aspiration (FNA). FNA pathology: Moderately differentiated adenocarcinoma. Immunohistochemistry suggestive of metastasis of the lower gastrointestinal tract. Due this finding, realized colonoscopy, which revealed a vegetating lesion with central ulceration, bleeding, filling almost the entire cecum. Patient was referred for surgical resection of the bowel tumor, which showed moderately differentiated adenocarcinoma infiltrating vegetative and possibly originated from villous adenoma with high-grade dysplasia. DISCUSSION: The finding of metastatic liver abscess of colonic neoplasia is not common. In most cases, the material from the abscess drainage allows the diagnosis, but in this case, even after two ultrasound-guided percutaneous drainage was not obtained conclusive bacteriological or histopathological. Opted for new puncture through EUS, which allowed definitive diagnosis of the condition. CONCLUSION: Metastatic colon neoplasm should be considered in cases of differential diagnosis of liver abscess. Medknow Publications & Media Pvt Ltd 2014-04 /pmc/articles/PMC4569906/ /pubmed/26425508 Text en Copyright: © Endoscopic Ultrasound http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle EURO EUS Meeting
Schneider, N. Camargo
Coelho, N.
Dutra, P.
Dalmolin, R.
Dincao, R.
Appel, M.
Liver abscess as a first manifestation of colonic tumor
title Liver abscess as a first manifestation of colonic tumor
title_full Liver abscess as a first manifestation of colonic tumor
title_fullStr Liver abscess as a first manifestation of colonic tumor
title_full_unstemmed Liver abscess as a first manifestation of colonic tumor
title_short Liver abscess as a first manifestation of colonic tumor
title_sort liver abscess as a first manifestation of colonic tumor
topic EURO EUS Meeting
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569906/
https://www.ncbi.nlm.nih.gov/pubmed/26425508
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