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Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation

OBJECTIVE: Echo-endoscopes are much stiffer and thicker than regular endoscopes. During the procedure of endoscopic ultrasound (EUS) procedure, water irrigation is a very useful for imaging but very dangerous if the patient receive the procedure under anesthesia without intubation. In this study, we...

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Autores principales: Wang, C., Sun, S., liu, X., Guo, J., Wang, S., Wang, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569912/
https://www.ncbi.nlm.nih.gov/pubmed/26425514
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author Wang, C.
Sun, S.
liu, X.
Guo, J.
Wang, S.
Wang, G.
author_facet Wang, C.
Sun, S.
liu, X.
Guo, J.
Wang, S.
Wang, G.
author_sort Wang, C.
collection PubMed
description OBJECTIVE: Echo-endoscopes are much stiffer and thicker than regular endoscopes. During the procedure of endoscopic ultrasound (EUS) procedure, water irrigation is a very useful for imaging but very dangerous if the patient receive the procedure under anesthesia without intubation. In this study, we evaluated the safety and effectiveness of nitrous oxide (N(2)O) (≤70%) for EUS. METHODS: Among 4230 patients who underwent EUS from December 2012 to December 2013, 347 out patients who need irrigation during the procedure were enrolled and divided into Group A. Group A (N(2)O sedation group, n = 162) and Group B (no sedative group, n = 185). For Group A, patients received N(2)O by inhalation during the procedure. The mixture rate of N(2)O and O(2) was 45-65% and controlled by nurses according to individual effect. The cardiorespiratory functions, procedure duration, complications, and visual analog scale (VAS) of the patient and examiner satisfaction were compared. RESULTS: Both group had comparable diagnostic accuracy, but VAS of the patients who received N(2)O sedation was higher than that in Group B (7.5 vs. 4.5, P < 0.05) and the examiner procedural satisfaction ratings of Group A was also better than that of Group B (8.1 vs. 5.1, P < 0.05); Most patients in Group A reported willingness to reconsider N(2)O for a future EUS. No pulmonary aspiration occurred in this study. CONCLUSIONS: N(2)O for EUS is comfortable, safe and feasible, especially for the procedures that need irrigation.
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spelling pubmed-45699122015-09-30 Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation Wang, C. Sun, S. liu, X. Guo, J. Wang, S. Wang, G. Endosc Ultrasound EURO EUS Meeting OBJECTIVE: Echo-endoscopes are much stiffer and thicker than regular endoscopes. During the procedure of endoscopic ultrasound (EUS) procedure, water irrigation is a very useful for imaging but very dangerous if the patient receive the procedure under anesthesia without intubation. In this study, we evaluated the safety and effectiveness of nitrous oxide (N(2)O) (≤70%) for EUS. METHODS: Among 4230 patients who underwent EUS from December 2012 to December 2013, 347 out patients who need irrigation during the procedure were enrolled and divided into Group A. Group A (N(2)O sedation group, n = 162) and Group B (no sedative group, n = 185). For Group A, patients received N(2)O by inhalation during the procedure. The mixture rate of N(2)O and O(2) was 45-65% and controlled by nurses according to individual effect. The cardiorespiratory functions, procedure duration, complications, and visual analog scale (VAS) of the patient and examiner satisfaction were compared. RESULTS: Both group had comparable diagnostic accuracy, but VAS of the patients who received N(2)O sedation was higher than that in Group B (7.5 vs. 4.5, P < 0.05) and the examiner procedural satisfaction ratings of Group A was also better than that of Group B (8.1 vs. 5.1, P < 0.05); Most patients in Group A reported willingness to reconsider N(2)O for a future EUS. No pulmonary aspiration occurred in this study. CONCLUSIONS: N(2)O for EUS is comfortable, safe and feasible, especially for the procedures that need irrigation. Medknow Publications & Media Pvt Ltd 2014-04 /pmc/articles/PMC4569912/ /pubmed/26425514 Text en Copyright: © Endoscopic Ultrasound http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle EURO EUS Meeting
Wang, C.
Sun, S.
liu, X.
Guo, J.
Wang, S.
Wang, G.
Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation
title Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation
title_full Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation
title_fullStr Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation
title_full_unstemmed Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation
title_short Safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation
title_sort safety and efficacy of nitrous oxide for endoscopic ultrasound procedures that need irrigation
topic EURO EUS Meeting
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569912/
https://www.ncbi.nlm.nih.gov/pubmed/26425514
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