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Dynamic control of pH in esophagus diseases treatment
During complete medical checkup of proximal gastrointestinal tract, the esophagus pH measurement is an adventive procedure that requires probes usage, which is introduced through the endoscope biopsy channel. Such procedure cannot be used for everyday dynamic treatment control because of its invasiv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569936/ https://www.ncbi.nlm.nih.gov/pubmed/26425536 |
Sumario: | During complete medical checkup of proximal gastrointestinal tract, the esophagus pH measurement is an adventive procedure that requires probes usage, which is introduced through the endoscope biopsy channel. Such procedure cannot be used for everyday dynamic treatment control because of its invasiveness. The main aim of this article is to develop an effective everyday quality control of esophagus diseases non-traumatic antisecretory treatment. We solve the problem by measuring the air-ionic esophagus internal environment characteristics with the help of the air exhaled by the patient analysis. Initial examination is provided during endoscopic research in the period of patient's planned checkup. Esophagus air tests are get through biopsy channel and analyzed by computer air-ionic complex. The range of air-ionic concentration in the esophagus air content is 0.060-0.040 (60-40%) in electrical voltage 0.020-0.050 V, which corresponds to pH 5.0-7.0. The esophagus air content indexes, received from primary samples are used as gauging for air-ionic characteristics of air exhausted by patient. Hereafter, during the therapy course we study only air samples exhausted by the patient on a daily basis. Air-ionic esophageal pH — measurement is used during checkup and treatment of 42 patients with gastroesophageal reflux disease diagnose. Parallel usage of invasive esophageal pH determination method demonstrated complete results match. Thus, the proposed method is an advanced non-invasive diagnostic method, which allows to measure intra-esophagus pH indexes and provides probable assessment of antisecretory drugs treatment efficacy with an ability of therapeutic course operative correction. |
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