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BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties
In a recent adoptive cell therapy (ACT) clinical trial using autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, we found an association between CD8(+) T cells expressing the inhibitory receptor B- and T-lymphocyte attenuator (BTLA) and clinical response. Here, we...
Autores principales: | Haymaker, Cara L, Wu, Richard C, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andrée, Chen, Jie Qing, Liu, Hui, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570103/ https://www.ncbi.nlm.nih.gov/pubmed/26405566 http://dx.doi.org/10.1080/2162402X.2015.1014246 |
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