Cargando…

The codon-optimized Δ(6)-desaturase gene of Pythium sp. as an empowering tool for engineering n3/n6 polyunsaturated fatty acid biosynthesis

BACKGROUND: The ∆(6)-desaturase gene, encoding a key enzyme in the biosynthesis of polyunsaturated fatty acids, has potential in pharmaceutical and nutraceutical applications. RESULTS: The ∆(6)-desaturase gene has been isolated from a selected strain of Oomycetes, Pythium sp. BCC53698. The cloned ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeennor, Sukanya, Cheawchanlertfa, Pattsarun, Suttiwattanakul, Sarinya, Panchanawaporn, Sarocha, Chutrakul, Chanikul, Laoteng, Kobkul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570148/ https://www.ncbi.nlm.nih.gov/pubmed/26369666 http://dx.doi.org/10.1186/s12896-015-0200-6

Ejemplares similares

Novel pentose-regulated promoter of Aspergillus oryzae with application in controlling heterologous gene expression
por: Jeennor, Sukanya, et al.
Publicado: (2021)

Potential of Aspergillus oryzae as a biosynthetic platform for indigoidine, a non-ribosomal peptide pigment with antioxidant activity
por: Panchanawaporn, Sarocha, et al.
Publicado: (2022)

The Exploring Functional Role of Ammonium Transporters of Aspergillus oryzae in Nitrogen Metabolism: Challenges towards Cell Biomass Production
por: Chutrakul, Chanikul, et al.
Publicado: (2022)

Systematic development of biomass overproducing Scheffersomyces stipitis for high-cell-density fermentations
por: Unrean, Pornkamol, et al.
Publicado: (2016)

Enhancing Genome-Scale Model by Integrative Exometabolome and Transcriptome: Unveiling Carbon Assimilation towards Sphingolipid Biosynthetic Capability of Cordyceps militaris
por: Cheawchanlertfa, Pattsarun, et al.
Publicado: (2022)

Survey of n-3 and n-6 polyunsaturated fatty acids in fish and fish products
por: Strobel, Claudia, et al.
Publicado: (2012)

Effects of Dietary n–3 and n–6 Polyunsaturated Fatty Acids in Inflammation and Cancerogenesis
por: Liput, Kamila P., et al.
Publicado: (2021)

Uncovering global metabolic response to cordycepin production in Cordyceps militaris through transcriptome and genome-scale network-driven analysis
por: Raethong, Nachon, et al.
Publicado: (2018)

Plasma Phospholipid n-3/n-6 Polyunsaturated Fatty Acids and Desaturase Activities in Relation to Moderate-to-Vigorous Physical Activity through Pregnancy: A Longitudinal Study within the NICHD Fetal Growth Studies
por: Chen, Liwei, et al.
Publicado: (2020)

Interaction among dietary n‐3 and n‐6 polyunsaturated fatty acid intake, fatty acid desaturase 2 genetic variants, and low‐density lipoprotein cholesterol levels in type 2 diabetes patients
por: Huang, Pei‐Chi, et al.
Publicado: (2022)

The effect of n-3/n-6 polyunsaturated fatty acids on acute reflux esophagitis in rats
por: Zhuang, Ze-Hao, et al.
Publicado: (2016)

Effects of the n-6/n-3 polyunsaturated fatty acids ratio on postprandial metabolism in hypertriacylglycerolemia patients
por: Song, Zhixiu, et al.
Publicado: (2013)

Effects of different dietary n-6/n-3 polyunsaturated fatty acid ratios on boar reproduction
por: Lin, Yan, et al.
Publicado: (2016)

Fatty Acid Desaturases, Polyunsaturated Fatty Acid Regulation, and Biotechnological Advances
por: Lee, Je Min, et al.
Publicado: (2016)

Her-2 Breast Cancer Outcomes Are Mitigated by Consuming n-3 Polyunsaturated, Saturated, and Monounsaturated Fatty Acids Compared to n-6 Polyunsaturated Fatty Acids
por: Hillyer, Lyn M., et al.
Publicado: (2020)

Statin treatment alters serum n-3 to n-6 polyunsaturated fatty acids ratio in patients with dyslipidemia
por: Nozue, Tsuyoshi, et al.
Publicado: (2015)

Retraction Note: The effect of n-3/n-6 polyunsaturated fatty acids on acute reflux esophagitis in rats
por: Zhuang, Ze-Hao, et al.
Publicado: (2023)

Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse
por: Monteiro, Jessica, et al.
Publicado: (2012)

Running Speed in Mammals Increases with Muscle n-6 Polyunsaturated Fatty Acid Content
por: Ruf, Thomas, et al.
Publicado: (2006)

N-6 polyunsaturated fatty acids in human breast carcinoma phosphatidylethanolamine and early relapse.
por: Lanson, M., et al.
Publicado: (1990)

Role of serum n-6 polyunsaturated fatty acids in the development of acute coronary syndromes
por: Inoue, Naoya, et al.
Publicado: (2023)

Sequence- and Structure-Based Functional Annotation and Assessment of Metabolic Transporters in Aspergillus oryzae: A Representative Case Study
por: Raethong, Nachon, et al.
Publicado: (2016)

Dietary n-3 Polyunsaturated Fatty Acid Intakes Modify the Effect of Genetic Variation in Fatty Acid Desaturase 1 on Coronary Artery Disease
por: Liu, Fengqiong, et al.
Publicado: (2015)

n3 and n6 polyunsaturated fatty acids differentially modulate prostaglandin E secretion but not markers of lipogenesis in adipocytes
por: Wortman, Patrick, et al.
Publicado: (2009)

Generation of Fad2 and Fad3 transgenic mice that produce n-6 and n-3 polyunsaturated fatty acids
por: Song, Lishuang, et al.
Publicado: (2019)

Associations of serum n–3 and n–6 polyunsaturated fatty acids with prevalence and incidence of nonalcoholic fatty liver disease
por: Mäkelä, Tiia N K, et al.
Publicado: (2022)

Metabolic Responses of Carotenoid and Cordycepin Biosynthetic Pathways in Cordyceps militaris under Light-Programming Exposure through Genome-Wide Transcriptional Analysis
por: Thananusak, Roypim, et al.
Publicado: (2020)

Physiological Traits of Dihomo-γ-Linolenic Acid Production of the Engineered Aspergillus oryzae by Comparing Mathematical Models
por: Antimanon, Sompot, et al.
Publicado: (2020)

Metabolic Regulation of Sugar Assimilation for Lipid Production in Aspergillus oryzae BCC7051 through Comparative Transcriptome Perspective
por: Vorapreeda, Tayvich, et al.
Publicado: (2021)

The effects of n-6 polyunsaturated fatty acids on the expression of nm-23 in human cancer cells.
por: Jiang, W. G., et al.
Publicado: (1998)

N-6 Polyunsaturated Fatty Acids and Risk of Cancer: Accumulating Evidence from Prospective Studies
por: Kim, Youngyo, et al.
Publicado: (2020)

Ratio of Dietary n-6/n-3 Polyunsaturated Fatty Acids Independently Related to Muscle Mass Decline in Hemodialysis Patients
por: Wong, Te-Chih, et al.
Publicado: (2015)

Dietary n-3 and n-6 polyunsaturated fatty acids, the FADS gene, and the risk of gastric cancer in a Korean population
por: Lee, Sunghee, et al.
Publicado: (2018)

Interplay Between n-3 and n-6 Long-Chain Polyunsaturated Fatty Acids and the Endocannabinoid System in Brain Protection and Repair
por: Dyall, Simon C.
Publicado: (2017)

Azacarbazole n-3 and n-6 polyunsaturated fatty acids ethyl esters nanoemulsion with enhanced efficacy against Plasmodium falciparum
por: Jaromin, Anna, et al.
Publicado: (2020)

Δ12-Fatty Acid Desaturase from Candida parapsilosis Is a Multifunctional Desaturase Producing a Range of Polyunsaturated and Hydroxylated Fatty Acids
por: Buček, Aleš, et al.
Publicado: (2014)

Dual-Transcriptomic, Microscopic, and Biocontrol Analyses of the Interaction Between the Bioeffector Pythium oligandrum and the Pythium Soft-Rot of Ginger Pathogen Pythium myriotylum
por: Daly, Paul, et al.
Publicado: (2021)

High fat / high cholesterol diet does not provoke atherosclerosis in the ω3-and ω6-polyunsaturated fatty acid synthesis–inactivated Δ6-fatty acid desaturase–deficient mouse
por: Stoffel, Wilhelm, et al.
Publicado: (2021)

Unusually High Levels of n-6 Polyunsaturated Fatty Acids in Whale Sharks and Reef Manta Rays
por: Couturier, L. I. E., et al.
Publicado: (2013)

The effects of n-6 polyunsaturated fatty acid deprivation on the inflammatory gene response to lipopolysaccharide in the mouse hippocampus
por: Alashmali, Shoug M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8ao5bvcceico4ufnfaug7in4db