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Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
BACKGROUND: Osteomyelitis is a challenge for orthopaedic surgeons. There is a lack of scientific evidence to guide treatment. The purpose of this study was to report the clinical outcome of unplanned retention of antibiotic-impregnated cement spacer (ACS) in the management of osteomyelitis. METHODS:...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570462/ https://www.ncbi.nlm.nih.gov/pubmed/26370895 http://dx.doi.org/10.1186/s12891-015-0704-1 |
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author | Qiu, Xu-Sheng Zheng, Xin Shi, Hong-fei Zhu, Yan-cheng Guo, Xia Mao, Hai-jun Xu, Guang-yue Chen, Yi-xin |
author_facet | Qiu, Xu-Sheng Zheng, Xin Shi, Hong-fei Zhu, Yan-cheng Guo, Xia Mao, Hai-jun Xu, Guang-yue Chen, Yi-xin |
author_sort | Qiu, Xu-Sheng |
collection | PubMed |
description | BACKGROUND: Osteomyelitis is a challenge for orthopaedic surgeons. There is a lack of scientific evidence to guide treatment. The purpose of this study was to report the clinical outcome of unplanned retention of antibiotic-impregnated cement spacer (ACS) in the management of osteomyelitis. METHODS: Eight patients (7 with tibial infections and 1 with a calcaneal infection) with osteomyelitis received radical debridement and insertion of an ACS into the bone defect as the definitive management. The mean follow-up period was 2 years (6 months to 4 years). All of these patients had a cement spacer in place. RESULTS: No patient exhibited radiographic evidence of excessive bone loss. The patients reported no or occasional mild pain and exhibited complete weight-bearing abilities, with the exception of one patient who required a crutch because of a spinal cord injury. Signs of recurrence of the osteomyelitis were not noted in any of the patients, and no fractures occurred at last follow-up. CONCLUSION: Our study suggests that a proportion of patients with unplanned retention of ACS appear to function well without necessarily requiring further surgical intervention. |
format | Online Article Text |
id | pubmed-4570462 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-45704622015-09-16 Antibiotic-impregnated cement spacer as definitive management for osteomyelitis Qiu, Xu-Sheng Zheng, Xin Shi, Hong-fei Zhu, Yan-cheng Guo, Xia Mao, Hai-jun Xu, Guang-yue Chen, Yi-xin BMC Musculoskelet Disord Research Article BACKGROUND: Osteomyelitis is a challenge for orthopaedic surgeons. There is a lack of scientific evidence to guide treatment. The purpose of this study was to report the clinical outcome of unplanned retention of antibiotic-impregnated cement spacer (ACS) in the management of osteomyelitis. METHODS: Eight patients (7 with tibial infections and 1 with a calcaneal infection) with osteomyelitis received radical debridement and insertion of an ACS into the bone defect as the definitive management. The mean follow-up period was 2 years (6 months to 4 years). All of these patients had a cement spacer in place. RESULTS: No patient exhibited radiographic evidence of excessive bone loss. The patients reported no or occasional mild pain and exhibited complete weight-bearing abilities, with the exception of one patient who required a crutch because of a spinal cord injury. Signs of recurrence of the osteomyelitis were not noted in any of the patients, and no fractures occurred at last follow-up. CONCLUSION: Our study suggests that a proportion of patients with unplanned retention of ACS appear to function well without necessarily requiring further surgical intervention. BioMed Central 2015-09-14 /pmc/articles/PMC4570462/ /pubmed/26370895 http://dx.doi.org/10.1186/s12891-015-0704-1 Text en © Qiu et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Qiu, Xu-Sheng Zheng, Xin Shi, Hong-fei Zhu, Yan-cheng Guo, Xia Mao, Hai-jun Xu, Guang-yue Chen, Yi-xin Antibiotic-impregnated cement spacer as definitive management for osteomyelitis |
title | Antibiotic-impregnated cement spacer as definitive management for osteomyelitis |
title_full | Antibiotic-impregnated cement spacer as definitive management for osteomyelitis |
title_fullStr | Antibiotic-impregnated cement spacer as definitive management for osteomyelitis |
title_full_unstemmed | Antibiotic-impregnated cement spacer as definitive management for osteomyelitis |
title_short | Antibiotic-impregnated cement spacer as definitive management for osteomyelitis |
title_sort | antibiotic-impregnated cement spacer as definitive management for osteomyelitis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570462/ https://www.ncbi.nlm.nih.gov/pubmed/26370895 http://dx.doi.org/10.1186/s12891-015-0704-1 |
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