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Antibiotic-impregnated cement spacer as definitive management for osteomyelitis

BACKGROUND: Osteomyelitis is a challenge for orthopaedic surgeons. There is a lack of scientific evidence to guide treatment. The purpose of this study was to report the clinical outcome of unplanned retention of antibiotic-impregnated cement spacer (ACS) in the management of osteomyelitis. METHODS:...

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Autores principales: Qiu, Xu-Sheng, Zheng, Xin, Shi, Hong-fei, Zhu, Yan-cheng, Guo, Xia, Mao, Hai-jun, Xu, Guang-yue, Chen, Yi-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570462/
https://www.ncbi.nlm.nih.gov/pubmed/26370895
http://dx.doi.org/10.1186/s12891-015-0704-1
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author Qiu, Xu-Sheng
Zheng, Xin
Shi, Hong-fei
Zhu, Yan-cheng
Guo, Xia
Mao, Hai-jun
Xu, Guang-yue
Chen, Yi-xin
author_facet Qiu, Xu-Sheng
Zheng, Xin
Shi, Hong-fei
Zhu, Yan-cheng
Guo, Xia
Mao, Hai-jun
Xu, Guang-yue
Chen, Yi-xin
author_sort Qiu, Xu-Sheng
collection PubMed
description BACKGROUND: Osteomyelitis is a challenge for orthopaedic surgeons. There is a lack of scientific evidence to guide treatment. The purpose of this study was to report the clinical outcome of unplanned retention of antibiotic-impregnated cement spacer (ACS) in the management of osteomyelitis. METHODS: Eight patients (7 with tibial infections and 1 with a calcaneal infection) with osteomyelitis received radical debridement and insertion of an ACS into the bone defect as the definitive management. The mean follow-up period was 2 years (6 months to 4 years). All of these patients had a cement spacer in place. RESULTS: No patient exhibited radiographic evidence of excessive bone loss. The patients reported no or occasional mild pain and exhibited complete weight-bearing abilities, with the exception of one patient who required a crutch because of a spinal cord injury. Signs of recurrence of the osteomyelitis were not noted in any of the patients, and no fractures occurred at last follow-up. CONCLUSION: Our study suggests that a proportion of patients with unplanned retention of ACS appear to function well without necessarily requiring further surgical intervention.
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spelling pubmed-45704622015-09-16 Antibiotic-impregnated cement spacer as definitive management for osteomyelitis Qiu, Xu-Sheng Zheng, Xin Shi, Hong-fei Zhu, Yan-cheng Guo, Xia Mao, Hai-jun Xu, Guang-yue Chen, Yi-xin BMC Musculoskelet Disord Research Article BACKGROUND: Osteomyelitis is a challenge for orthopaedic surgeons. There is a lack of scientific evidence to guide treatment. The purpose of this study was to report the clinical outcome of unplanned retention of antibiotic-impregnated cement spacer (ACS) in the management of osteomyelitis. METHODS: Eight patients (7 with tibial infections and 1 with a calcaneal infection) with osteomyelitis received radical debridement and insertion of an ACS into the bone defect as the definitive management. The mean follow-up period was 2 years (6 months to 4 years). All of these patients had a cement spacer in place. RESULTS: No patient exhibited radiographic evidence of excessive bone loss. The patients reported no or occasional mild pain and exhibited complete weight-bearing abilities, with the exception of one patient who required a crutch because of a spinal cord injury. Signs of recurrence of the osteomyelitis were not noted in any of the patients, and no fractures occurred at last follow-up. CONCLUSION: Our study suggests that a proportion of patients with unplanned retention of ACS appear to function well without necessarily requiring further surgical intervention. BioMed Central 2015-09-14 /pmc/articles/PMC4570462/ /pubmed/26370895 http://dx.doi.org/10.1186/s12891-015-0704-1 Text en © Qiu et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Qiu, Xu-Sheng
Zheng, Xin
Shi, Hong-fei
Zhu, Yan-cheng
Guo, Xia
Mao, Hai-jun
Xu, Guang-yue
Chen, Yi-xin
Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
title Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
title_full Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
title_fullStr Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
title_full_unstemmed Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
title_short Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
title_sort antibiotic-impregnated cement spacer as definitive management for osteomyelitis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570462/
https://www.ncbi.nlm.nih.gov/pubmed/26370895
http://dx.doi.org/10.1186/s12891-015-0704-1
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