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Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma

BACKGROUND: We evaluated candidate circulating serum cytokines, chemokines and growth factors in patients with locally/regionally advanced melanoma receiving neoadjuvant ipilimumab with toxicity and clinical outcome. METHODS: Patients were treated with ipilimumab (10 mg/kg IV every 3 weeks, 2 doses)...

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Detalles Bibliográficos
Autores principales:	Tarhini, Ahmad A., Zahoor, Haris, Lin, Yan, Malhotra, Usha, Sander, Cindy, Butterfield, Lisa H., Kirkwood, John M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570556/ https://www.ncbi.nlm.nih.gov/pubmed/26380086 http://dx.doi.org/10.1186/s40425-015-0081-1

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