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Finite mixture clustering of human tissues with different levels of IGF-1 splice variants mRNA transcripts

BACKGROUND: This study addresses a recurrent biological problem, that is to define a formal clustering structure for a set of tissues on the basis of the relative abundance of multiple alternatively spliced isoforms mRNAs generated by the same gene. To this aim, we have used a model-based clustering...

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Detalles Bibliográficos
Autores principales: Pelosi, Michele, Alfò, Marco, Martella, Francesca, Pappalardo, Elisa, Musarò, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570607/
https://www.ncbi.nlm.nih.gov/pubmed/26370240
http://dx.doi.org/10.1186/s12859-015-0689-7