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Finite mixture clustering of human tissues with different levels of IGF-1 splice variants mRNA transcripts
BACKGROUND: This study addresses a recurrent biological problem, that is to define a formal clustering structure for a set of tissues on the basis of the relative abundance of multiple alternatively spliced isoforms mRNAs generated by the same gene. To this aim, we have used a model-based clustering...
Autores principales: | Pelosi, Michele, Alfò, Marco, Martella, Francesca, Pappalardo, Elisa, Musarò, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570607/ https://www.ncbi.nlm.nih.gov/pubmed/26370240 http://dx.doi.org/10.1186/s12859-015-0689-7 |
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