Negatively charged AuNP modified with monoclonal antibody against novel tumor antigen FAT1 for tumor targeting

BACKGROUND: Herein, we demonstrated the use of a newly generated anti FAT1 antibody (clone mAB198.3) for intracellular delivery of anionic gold NPs, to form active targeting Au nanoparticles with high payload characteristics. METHODS: In vitro characterizations were determined by DLS, confocal micro...

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Detalles Bibliográficos
Autores principales: Fan, Li, Campagnoli, Susanna, Wu, Hong, Grandi, Alberto, Parri, Matteo, De Camilli, Elisa, Grandi, Guido, Viale, Giuseppe, Pileri, Piero, Grifantini, Renata, Song, Chaojun, Jin, Boquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570718/
https://www.ncbi.nlm.nih.gov/pubmed/26373379
http://dx.doi.org/10.1186/s13046-015-0214-x

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