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Intrathecal trastuzumab: immunotherapy improves the prognosis of leptomeningeal metastases in HER-2+ breast cancer patient

We describe the clinical and therapeutic course of a 51-year-old woman with HER-2+ breast cancer who developed leptomeningeal (LM) and spinal cord metastases after 8 years of stable disease on combination therapy with intravenous (IV) trastuzumab. Due to progressive CNS disease, intrathecal (IT) tra...

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Detalles Bibliográficos
Autores principales:	Lu, Nu T., Raizer, Jeffrey, Gabor, Erwin P., Liu, Natalie M., Vu, James Q., Slamon, Dennis J., Barstis, John L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Case Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570757/ https://www.ncbi.nlm.nih.gov/pubmed/26380087 http://dx.doi.org/10.1186/s40425-015-0084-y

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