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Characterisation of a Novel Anti-CD52 Antibody with Improved Efficacy and Reduced Immunogenicity
Anti-CD52 therapy has been shown to be effective in the treatment of a number of B cell malignancies, hematopoietic disorders and autoimmune diseases (including rheumatoid arthritis and multiple sclerosis); however the current standard of treatment, the humanized monoclonal antibody alemtuzumab, is...
Autores principales: | Holgate, Robert G. E., Weldon, Richard, Jones, Timothy D., Baker, Matthew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570798/ https://www.ncbi.nlm.nih.gov/pubmed/26372145 http://dx.doi.org/10.1371/journal.pone.0138123 |
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