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Role of XmnI(G) Polymorphism in Hydroxyurea Treatment and Fetal Hemoglobin Level at Isfahanian Intermediate β-Thalassemia Patients

BACKGROUND: β-thalassemia is the most common monogenic disorder in human. The (CT) polymorphism at -158 upstream region of the γ(G)-globin gene and pharmacological factors such as hydroxyurea have been reported to influence γ-globin gene expression and the severity of clinical symptoms of β-thalasse...

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Detalles Bibliográficos
Autores principales:	Motovali-Bashi, Majid, Ghasemi, Tayyebeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pasteur Institute of Iran 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571014/ https://www.ncbi.nlm.nih.gov/pubmed/26024726 http://dx.doi.org/10.7508/ibj.2015.03.008

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