Simultaneous quantification of salivary 3-hydroxybutyrate, 3-hydroxyisobutyrate, 3-hydroxy-3-methylbutyrate, and 2-hydroxybutyrate as possible markers of amino acid and fatty acid catabolic pathways by LC–ESI–MS/MS

We have developed a highly sensitive and specific method for quantification of salivary 3-hydroxybutyrate (3HB), 3-hydroxyisobutyrate (3HIB), 3-hydroxy-3-methylbutyrate (3HMB) and 2-hydroxybutyrate (2HB), which could be new non-invasive biomarkers for catabolic pathways of fatty acids/ketogenic amin...

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Detalles Bibliográficos
Autores principales: Miyazaki, Teruo, Honda, Akira, Ikegami, Tadashi, Iwamoto, Junichi, Monma, Tadakuni, Hirayama, Takeshi, Saito, Yoshifumi, Yamashita, Kouwa, Matsuzaki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571036/
https://www.ncbi.nlm.nih.gov/pubmed/26389019
http://dx.doi.org/10.1186/s40064-015-1304-0

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