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Intracellular expression of Tat alters mitochondrial functions in T cells: a potential mechanism to understand mitochondrial damage during HIV-1 replication

BACKGROUND: HIV-1 replication results in mitochondrial damage that is enhanced during antiretroviral therapy (ART). The onset of HIV-1 replication is regulated by viral protein Tat, a 101-residue protein codified by two exons that elongates viral transcripts. Although the first exon of Tat (aa 1–72)...

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Detalles Bibliográficos
Autores principales:	Rodríguez-Mora, Sara, Mateos, Elena, Moran, María, Martín, Miguel Ángel, López, Juan Antonio, Calvo, Enrique, Terrón, María Carmen, Luque, Daniel, Muriaux, Delphine, Alcamí, José, Coiras, Mayte, López-Huertas, María Rosa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571071/ https://www.ncbi.nlm.nih.gov/pubmed/26376973 http://dx.doi.org/10.1186/s12977-015-0203-3

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