Variation in Dube3a expression affects neurotransmission at the Drosophila neuromuscular junction

Changes in UBE3A expression levels in neurons can cause neurogenetic disorders ranging from Angelman syndrome (AS) (decreased levels) to autism (increased levels). Here we investigated the effects on neuronal function of varying UBE3A levels using the Drosophila neuromuscular junction as a model for...

Descripción completa

Detalles Bibliográficos
Autores principales: Valdez, Colleen, Scroggs, Reese, Chassen, Rachel, Reiter, Lawrence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571101/
https://www.ncbi.nlm.nih.gov/pubmed/25948754
http://dx.doi.org/10.1242/bio.20148045

Ejemplares similares

Ejemplares similares