Human Cancer Antigen Globo H Is a Cell-Surface Ligand for Human Ribonuclease 1

[Image: see text] Pancreatic-type ribonucleases are secretory enzymes that catalyze the cleavage of RNA. Recent efforts have endowed the homologues from cow (RNase A) and human (RNase 1) with toxicity for cancer cells, leading to a clinical trial. The basis for the selective toxicity of ribonuclease...

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Detalles Bibliográficos
Autores principales: Eller, Chelcie H., Chao, Tzu-Yuan, Singarapu, Kiran K., Ouerfelli, Ouathek, Yang, Guangbin, Markley, John L., Danishefsky, Samuel J., Raines, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571170/
https://www.ncbi.nlm.nih.gov/pubmed/26405690
http://dx.doi.org/10.1021/acscentsci.5b00164

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