Tumor suppressor protein Lgl mediates G1 cell cycle arrest at high cell density by forming an Lgl-VprBP-DDB1 complex

Lethal giant larvae (Lgl) is an evolutionarily conserved tumor suppressor whose loss of function causes disrupted epithelial architecture with enhanced cell proliferation and defects in cell polarity. A role for Lgl in the establishment and maintenance of cell polarity via suppression of the PAR-aPK...

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Detalles Bibliográficos
Autores principales: Yamashita, Kazunari, Ide, Mariko, Furukawa, Kana T., Suzuki, Atsushi, Hirano, Hisashi, Ohno, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571298/
https://www.ncbi.nlm.nih.gov/pubmed/25947136
http://dx.doi.org/10.1091/mbc.E14-10-1462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571298/
https://www.ncbi.nlm.nih.gov/pubmed/25947136
http://dx.doi.org/10.1091/mbc.E14-10-1462

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