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MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell–cell junctions in epithelial cells

Localized activation of Rho GTPases is essential for multiple cellular functions, including cytokinesis and formation and maintenance of cell–cell junctions. Although MgcRacGAP (Mgc) is required for spatially confined RhoA-GTP at the equatorial cortex of dividing cells, both the target specificity o...

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Detalles Bibliográficos
Autores principales:	Breznau, Elaina B., Semack, Ansley C., Higashi, Tomohito, Miller, Ann L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571299/ https://www.ncbi.nlm.nih.gov/pubmed/25947135 http://dx.doi.org/10.1091/mbc.E14-11-1553

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