Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

ERK-regulated cell proliferation requires multiple phosphorylation events catalyzed first by MEK and then by casein kinase 2 (CK2), followed by interaction with importin7 and subsequent nuclear translocation of pERK. We report that genetic manipulation of a core component of the actin filaments of c...

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Detalles Bibliográficos
Autores principales: Schevzov, Galina, Kee, Anthony J., Wang, Bin, Sequeira, Vanessa B., Hook, Jeff, Coombes, Jason D., Lucas, Christine A., Stehn, Justine R., Musgrove, Elizabeth A., Cretu, Alexandra, Assoian, Richard, Fath, Thomas, Hanoch, Tamar, Seger, Rony, Pleines, Irina, Kile, Benjamin T., Hardeman, Edna C., Gunning, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571302/
https://www.ncbi.nlm.nih.gov/pubmed/25971798
http://dx.doi.org/10.1091/mbc.E14-10-1453

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