Cargando…
Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning
Casein kinase 1δ (CK1δ) family members associate with microtubule-organizing centers (MTOCs) from yeast to humans, but their mitotic roles and targets have yet to be identified. We show here that budding yeast CK1δ, Hrr25, is a γ-tubulin small complex (γTuSC) binding factor. Moreover, Hrr25's a...
Autores principales: | Peng, Yutian, Moritz, Michelle, Han, Xuemei, Giddings, Thomas H., Lyon, Andrew, Kollman, Justin, Winey, Mark, Yates, John, Agard, David A., Drubin, David G., Barnes, Georjana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571304/ https://www.ncbi.nlm.nih.gov/pubmed/25971801 http://dx.doi.org/10.1091/mbc.E14-12-1627 |
Ejemplares similares
-
Microtubule nucleating γTuSC assembles structures with 13-fold microtubule-like symmetry
por: Kollman, Justin M., et al.
Publicado: (2010) -
Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC–spindle interaction to ensure proper microtubule dynamics
por: Nakajima, Yuko, et al.
Publicado: (2011) -
Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability
por: Choy, John S., et al.
Publicado: (2013) -
The microtubule polymerase Stu2 promotes oligomerization of the γ-TuSC for cytoplasmic microtubule nucleation
por: Gunzelmann, Judith, et al.
Publicado: (2018) -
Overlapping kinetochore targets of CK2 and Aurora B kinases in mitotic regulation
por: Peng, Yutian, et al.
Publicado: (2011)