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Tetramethylpyrazine Produces Antidepressant-Like Effects in Mice Through Promotion of BDNF Signaling Pathway

BACKGROUND: Current antidepressants are clinically effective only after several weeks of administration. Tetramethylpyrazine (TMP) is an identified component of Ligusticum wallichii with neuroprotective effects. Here, we investigated the antidepressant effects of TMP in mice models of depression. ME...

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Detalles Bibliográficos
Autores principales:	Jiang, Bo, Huang, Chao, Chen, Xiang-Fan, Tong, Li-Juan, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571627/ https://www.ncbi.nlm.nih.gov/pubmed/25618406 http://dx.doi.org/10.1093/ijnp/pyv010

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