Cargando…

An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP

TCF/LEF factors are ancient context-dependent enhancer-binding proteins that are activated by β-catenin following Wnt signaling. They control embryonic development and adult stem cell compartments, and their dysregulation often causes cancer. β-catenin-dependent transcription relies on the NPF motif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fiedler, Marc, Graeb, Michael, Mieszczanek, Juliusz, Rutherford, Trevor J, Johnson, Christopher M, Bienz, Mariann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571689/ https://www.ncbi.nlm.nih.gov/pubmed/26312500 http://dx.doi.org/10.7554/eLife.09073

Ejemplares similares

Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome
por: Renko, Miha, et al.
Publicado: (2019)

Structural basis of the interaction between BCL9-Pygo and LDB-SSBP complexes in assembling the Wnt enhanceosome
por: Wang, Hongyang, et al.
Publicado: (2023)

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9
por: van Tienen, Laurens M, et al.
Publicado: (2017)

Correction: Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9
por: van Tienen, Laurens M, et al.
Publicado: (2017)

Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex
por: Fiedler, Marc, et al.
Publicado: (2008)

Evolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2
por: Miller, Thomas C.R., et al.
Publicado: (2013)

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models
por: Mieszczanek, Juliusz, et al.
Publicado: (2019)

Planarian LDB and SSDP proteins scaffold transcriptional complexes for regeneration and patterning
por: Medlock-Lanier, Taylor, et al.
Publicado: (2023)

Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo PHD Finger
por: Miller, Thomas C. R., et al.
Publicado: (2014)

Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling
por: Mieszczanek, Juliusz, et al.
Publicado: (2022)

Allosteric Remodelling of the Histone H3 Binding Pocket in the Pygo2 PHD Finger Triggered by Its Binding to the B9L/BCL9 Co-Factor
por: Miller, Thomas C.R., et al.
Publicado: (2010)

Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled
por: Mund, Thomas, et al.
Publicado: (2015)

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5
por: Flack, Joshua E., et al.
Publicado: (2017)

Feedback control of Wnt signaling based on ultrastable histidine cluster co-aggregation between Naked/NKD and Axin
por: Gammons, Melissa V, et al.
Publicado: (2020)

The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled
por: Mendoza-Topaz, Carolina, et al.
Publicado: (2011)

Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction
por: Kan, Wei, et al.
Publicado: (2020)

Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development
por: Schwab, Kristopher R, et al.
Publicado: (2007)

Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly
por: He, Ju, et al.
Publicado: (2011)

Tomography gives a new dimension to an ancient organelle
por: Silva, Malan, et al.
Publicado: (2014)

Transcriptional Regulation by CHIP/LDB Complexes
por: Bronstein, Revital, et al.
Publicado: (2010)

Correction: Transcriptional Regulation by CHIP/LDB Complexes
por: Bronstein, Revital, et al.
Publicado: (2011)

Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled
por: Gammons, Melissa V., et al.
Publicado: (2016)

Epigenetics, Wnt signaling, and stem cells: the Pygo2 connection
por: Horsley, Valerie
Publicado: (2009)

Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways
por: Lee, Ho-Jin, et al.
Publicado: (2015)

Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan
por: Chang, Tao-Hsin, et al.
Publicado: (2015)

Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling
por: Aznar, Nicolas, et al.
Publicado: (2015)

Intracellular shuttling of a Drosophila APC tumour suppressor homolog
por: Cliffe, Adam, et al.
Publicado: (2004)

Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter
por: Steiner, Julia, et al.
Publicado: (2020)

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay
por: Gammons, Melissa V., et al.
Publicado: (2016)

From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics
por: Ingber, Donald E.
Publicado: (2023)

An Ankyrin-repeat ubiquitin binding domain determines TRABID’s specificity for atypical ubiquitin chains
por: Licchesi, Julien D.F., et al.
Publicado: (2011)

Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
por: Huber, Stefan T, et al.
Publicado: (2022)

Enzyme activity and selectivity filter stability of ancient TRPM2 channels were simultaneously lost in early vertebrates
por: Iordanov, Iordan, et al.
Publicado: (2019)

ResSKNet-SSDP: Effective and Light End-To-End Architecture for Speaker Recognition
por: Deng, Fei, et al.
Publicado: (2023)

Plant vernalization proteins contain unusual PHD superdomains without histone H3 binding activity
por: Franco-Echevarría, Elsa, et al.
Publicado: (2022)

Spermatozoa scattering by a microchannel feature: an elastohydrodynamic model
por: Montenegro-Johnson, T. D., et al.
Publicado: (2015)

Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling
por: Tsutsumi, Naotaka, et al.
Publicado: (2020)

Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly
por: Cottee, Matthew A, et al.
Publicado: (2013)

The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies
por: Cottee, Matthew A, et al.
Publicado: (2015)

Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction
por: Elwell, Cherilyn A, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s7o2ji6fv46iar9khgb5olpvg7