Jagged1 intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart

AIMS: Notch1 signalling in the heart is mainly activated via expression of Jagged1 on the surface of cardiomyocytes. Notch controls cardiomyocyte proliferation and differentiation in the developing heart and regulates cardiac remodelling in the stressed adult heart. Besides canonical Notch receptor...

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Detalles Bibliográficos
Autores principales: Metrich, Mélanie, Bezdek Pomey, April, Berthonneche, Corinne, Sarre, Alexandre, Nemir, Mohamed, Pedrazzini, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571837/
https://www.ncbi.nlm.nih.gov/pubmed/26249804
http://dx.doi.org/10.1093/cvr/cvv209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571837/
https://www.ncbi.nlm.nih.gov/pubmed/26249804
http://dx.doi.org/10.1093/cvr/cvv209

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