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Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System

Previous studies reported the reconstitution of an Mlh1-Pms1-independent 5′ nick-directed mismatch repair (MMR) reaction using Saccharomyces cerevisiae proteins. Here we describe the reconstitution of a mispair-dependent Mlh1-Pms1 endonuclease activation reaction requiring Msh2-Msh6 (or Msh2-Msh3),...

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Detalles Bibliográficos
Autores principales:	Smith, Catherine E., Bowen, Nikki, Graham, William J., Goellner, Eva M., Srivatsan, Anjana, Kolodner, Richard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2015
Materias:	DNA and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571882/ https://www.ncbi.nlm.nih.gov/pubmed/26170454 http://dx.doi.org/10.1074/jbc.M115.662189

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